Panthenol ikomoka kuri vitamine B5, izwi kandi nka retinol B5. Vitamine B5, izwi kandi nka acide pantothenique, ifite imiterere idahindagurika kandi igira ingaruka ku bushyuhe no kuyikora, bigatuma igabanuka rya bioavailable. Kubwibyo, ibibanziriza, panthenol, ikoreshwa muburyo bwo kwisiga.
Ugereranije na vitamine B5 / acide pantothenike, panthenol ifite imiterere ihamye ifite uburemere bwa molekile ifite 205. Gusa irashobora kwinjira neza muri stratum corneum kandi igahita ihinduka vitamine B5, kikaba ari igice cyingenzi cyimikorere yumubiri ndetse nibikoresho byingenzi. kuri synthesis ya coenzyme A.CoenzymeA ni ibintu bifasha muburyo butandukanye bwa enzyme reaction mumubiri. Ifite uruhare mu ngirabuzimafatizo ya selile, itanga imbaraga mubikorwa byubuzima bwumubiri. Byongeye kandi, igira kandi uruhare muri metabolism yibice bitandukanye byingenzi bigize uruhu, nka cholesterol, aside irike, hamwe na synthesis ya sphingolipide.
Gukoresha panthenol kuruhu byatangiye mu 1944 kandi bifite amateka yimyaka irenga 70. Ikoreshwa cyane cyane mu kwisiga kugirango ibe nziza, ituje, kandi isanwe.
Uruhare runini
Ubushuheno kunoza inzitizi
Panthenol ubwayo ifite imirimo yo kwinjiza no kugumana, mu gihe iteza imbere synthesis ya lipide, kongera umuvuduko wa molekile ya lipide na microfilaments ya keratin, kunoza ibidukikije bigoye hagati ya keratinocytes, no gufasha gukomeza gukora neza inzitizi z’uruhu. Twabibutsa ko kugirango panthenol irusheho kunoza inzitizi, kwibandaho bigomba kuba 1% cyangwa hejuru, naho ubundi 0.5% birashobora kuba ingaruka nziza.
Guhumuriza
Ingaruka zo guhumuriza panthenol ahanini ituruka kubintu bibiri: ① kurinda ibyangiritse byangiza okiside ② kugabanya ibisubizo byumuriro
① Panthenol irashobora kugabanya umusaruro wubwoko bwa ogisijeni ikora mungirangingo zuruhu, mugihe hagenzurwa uburyo bwihariye bwa antioxydeant yuruhu, harimo no gutera ingirabuzimafatizo zuruhu kugirango zigaragaze ibintu byinshi birwanya umubiri - heme ogisijene-1 (HO-1), bityo byongere imbaraga za antioxydeant y'uruhu aside Pantothenique irashobora kugabanya igisubizo. Nyuma yo gukangura keratinocytes hamwe na capsaicin, kurekura ibintu bitera IL-6 na IL-8 byiyongera cyane. Ariko, nyuma yo kuvurwa na acide pantothenique, kurekura ibintu bitera umuriro birashobora kubuzwa, bityo bikagabanya ibisubizo byumuriro kandi bikagabanya uburibwe.
Teza imberegusana
Iyo ubunini bwa panthenol buri hagati ya 2% na 5%, birashobora guteza imbere kuvugurura uruhu rwabantu rwangiritse. Nyuma yo kuvura urugero rwimvune ya laser hamwe na panthenol, imvugo ya Ki67, ikimenyetso cyo gukwirakwiza keratinocyte, yariyongereye, byerekana ko keratinocytes nyinshi yinjiye muri leta ikwirakwiza kandi igatera icyorezo cya epidermal. Hagati aho, imvugo ya filaggrin, ikimenyetso cyingenzi cyo gutandukanya keratinocyte no gukora inzitizi, nayo yariyongereye, byerekana guteza imbere gusana inzitizi zuruhu. Ubushakashatsi bushya bwakozwe muri 2019 bwerekanye ko panthenol itera gukira ibikomere vuba kurusha amavuta yubutare kandi ishobora no kunoza inkovu.
Igihe cyo kohereza: Kanama-30-2024
