Ergothionein (mercapto histidine trimethyl umunyu w'imbere)
Ergothionine(EGT) ni antioxydants isanzwe ishobora kurinda selile mumubiri wumuntu kandi nikintu gikomeye mumubiri.
Mu rwego rwo kwita ku ruhu, ergotamine ifite antioxydants ikomeye. Irashobora gutesha agaciro radicals yubuntu, kugabanya kwangirika kwa okiside, kurinda selile zuruhu ibintu bidukikije byo hanze, bifasha gutinda gusaza kwuruhu, no gukomeza ubworoherane bwuruhu hamwe nurumuri.
Usibye ibijyanye no kwita ku ruhu, ergotamine ifite n'ibisabwa mu nganda zimiti. Kurugero, mugutezimbere ibiyobyabwenge bimwe na bimwe, birashobora gukoreshwa nkibikoresho bifasha kugirango bifashe kuzamura umutekano ningaruka zibiyobyabwenge. Mu rwego rw'ibiribwa, hari n'ubushakashatsi bwerekana uburyo bwo kuyikoresha nk'inyongeramusaruro y'ibiribwa kugirango wongere antioxydants y'ibiribwa kandi wongere ubuzima bwayo.
Ergothionein ifite umutekano mwinshi. Mu bicuruzwa byita ku ruhu, kwibanda ku nyongeramusaruro mubisanzwe biratandukana bitewe nuburyo bukenewe nibicuruzwa, muri rusange kuva kuri 0.1% kugeza 5%.
Uruhare rw'ingenzi
Antioxidant
Ergothionein irashobora kwitwara vuba na radicals yubuntu kugirango ihindurwe mubintu bitagira ingaruka, kandi ntabwo byoroshye kubura. Mugihe kimwe, irashobora kugumana urwego rwizindi antioxydants (nkaVC na glutathione), bityo ukarinda selile zuruhu kwangirika kwa okiside.
Uburyo bwibikorwa byabwo ni ugusiba neza - OH (hydroxyl radicals), chelate ion ihwanye nicyuma hamwe na ion z'umuringa, kubuza H2O2 kubyara - OH hifashishijwe ibyuma bya ion cyangwa umuringa, kubuza ion ion y'umuringa biterwa na okiside ya ogisijeni ya hemoglobine, kandi ikanabuza. reaction ya peroxidation itera aside arachidonic nyuma ya myoglobine (cyangwa hemoglobine) ivanze na H2O2.
Kurwanya indwara
Igisubizo cyo gutwika mumubiri nigisubizo gisanzwe cyo kwirwanaho gitera imbaraga, kimwe no kwerekana ko umubiri urwanya ibintu byangiza. Ergothionein irashobora kubuza kubyara ibintu bitera umuriro, kugabanya urugero rwibisubizo byokongoka, no kugabanya uruhu rutameze neza. Ikora ingaruka zo kurwanya inflammatory muguhuza inzira zerekana ibimenyetso no guhagarika imiterere ya genes zijyanye no gutwika. Kurugero, kuburuhu rworoshye cyangwa acne, ergotamine irashobora gufasha kugabanya uburibwe no guteza imbere gusana uruhu.
Kurinda gufotora
Ergothionein irashobora gukumira ADN iterwa n'umucyo ultraviolet na hydrogène peroxide, kandi irashobora no gusibanganya radicals yubusa no kwinjiza imishwarara ya ultraviolet kugirango ikureho ADN. Muburyo bwo kwinjiza ultraviolet, ergothionein ifite uburebure bwumurongo busa nubwa ADN. Kubwibyo, ergothionein irashobora gukora nka filteri ya physiologique kumirasire ya ultraviolet.
Kugeza ubu, ubushakashatsi bwinshi bwerekanye ko ergotamine ari ikintu cyiza cyane cyizuba cyizuba gishobora kwirinda kwangirika kwuruhu rwa UV.
Teza imbere ibisekuruza bya poroteyine
Ergothionein irashobora guteza imbere ubwiyongere bwa fibroblast kandi igatera synthesis ya kolagen na elastine. Itezimbere imvugo ya genes ya kolagen hamwe na protein synthesis mugukora molekile zimwe zerekana ibimenyetso muri selile.
Igihe cyo kohereza: Kanama-08-2024
