Mu rwego rwa siyanse yo kwisiga, DL panthenol ni nkurufunguzo rukinguye umuryango wubuzima bwuruhu. Ibi bibanziriza vitamine B5, hamwe nubushuhe buhebuje, gusana, hamwe ningaruka zo kurwanya inflammatory, byahindutse ingirakamaro mubikorwa byingenzi byo kuvura uruhu. Iyi ngingo izacengera mu mayobera ya siyansi, agaciro kayo, hamwe nigihe kizaza cya DL panthenol.
1 od Kode ya siyansi yaDL panthenol
DL panthenol nuburyo bwamoko bwa panthenol, hamwe nizina ryimiti 2,4-dihydroxy-N - (3-hydroxypropyl) -3,3-dimethylbutanamide. Imiterere ya molekuline ikubiyemo itsinda rimwe ryibanze ryinzoga hamwe nitsinda rya kabiri ryinzoga, rikabaha hydrophilicity nziza kandi yoroheje.
Uburyo bwo guhindura uruhu nurufunguzo rwo gukora DL panthenol. Nyuma yo kwinjira mu ruhu, DL panthenol ihinduka vuba muri acide pantothenique (vitamine B5), igira uruhare mu gusanisha coenzyme A, bityo bikagira ingaruka kuri metabolisme ya aside irike no gukwirakwiza selile. Ubushakashatsi bwerekanye ko igipimo cyo guhindura DL panthenol muri epidermis gishobora kugera kuri 85%.
Uburyo bukuru bwibikorwa burimo kongera imikorere yinzitizi yuruhu, guteza imbere ikwirakwizwa rya selile epithelia, no kubuza kwifata. Ubushakashatsi bwakozwe bwerekana ko nyuma yo gukoresha ibicuruzwa birimo 5% DL panthenol mu byumweru 4, gutakaza amazi ya transdermal yuruhu bigabanukaho 40%, kandi ubunyangamugayo bwa stratum corneum bwateye imbere cyane.
2 application Gushyira mu bikorwa byinshiDL panthenol
Mu rwego rwo kuvomera, DL panthenol yongerera imbaraga za stratum corneum kandi ikongerera uruhu uruhu. Igeragezwa rya Clinical ryerekanye ko gukoresha moisturizer irimo DL panthenol mu masaha 8 byongera ubuhehere bwuruhu 50%.
Kubijyanye no gusana, DL panthenol irashobora guteza imbere ikwirakwizwa rya epidermal selile no kwihutisha imikorere ya barrière. Ubushakashatsi bwerekanye ko nyuma yo gukoresha ibicuruzwa birimo DL panthenol bishobora kugabanya igihe cyo gukira ibikomere 30%.
Kubitaho imitsi yoroheje, ingaruka za DL panthenol zo kurwanya no guhumuriza ziragaragara cyane. Ubushakashatsi bwerekanye ko DL panthenol ishobora kubuza kurekura ibintu bitera nka IL-6 na TNF - α, kugabanya umutuku wuruhu no kurakara.
Mu kwita kumisatsi, DL panthenol irashobora kwinjira mumisatsi no gusana keratine yangiritse. Nyuma yo gukoresha ibicuruzwa byita kumisatsi birimo DL panthenol mugihe cyibyumweru 12, imbaraga zo kuvunika umusatsi ziyongereyeho 35% naho ububengerane bwiyongereyeho 40%.
3 future Ibizaza bya DL panthenol
Ubuhanga bushya bwo gukora nka nanocarrier na liposomes byateje imbere cyane ituze na bioavailable yaDL panthenol. Kurugero, nanoemulisiyo irashobora kongera uruhu rwa DL panthenol inshuro 2.
Ubushakashatsi bukoreshwa mubuvuzi bukomeje kwiyongera. Ubushakashatsi buheruka kwerekana bwerekana ko DL panthenol ifite agaciro gakomeye mukuvura indwara zuruhu nka atopic dermatitis na psoriasis. Kurugero, gukoresha DL panthenol irimo formulaire kubarwayi barwaye dermatite ya atopic irashobora kugabanya amanota yo kwandura 50%.
Icyizere cy'isoko ni kinini. Biteganijwe ko mu 2025, isoko rya DL panthenol ku isi rizagera kuri miliyoni 350 z'amadolari y'Amerika, aho izamuka ry’umwaka rirenga 8%. Hamwe no kwiyongera kubintu byoroheje bikoreshwa mubaguzi, ahantu hashyirwa DL panthenol izakomeza kwaguka.
Kuvumbura no gukoresha DL panthenol byafunguye ibihe bishya byo kwita ku ruhu. Kuva kubushuhe no gusana kugeza anti-inflammatory no guhumuriza, kuva mubuvuzi bwo mumaso kugeza kwita kumubiri, ibi bintu byinshi bikora bihindura imyumvire yacu kubuzima bwuruhu. Mu bihe biri imbere, hamwe n’iterambere ry’ikoranabuhanga rishyirwaho hamwe n’ubushakashatsi bwimbitse bw’ubuvuzi, DL panthenol nta gushidikanya ko izazana udushya twinshi ndetse n’uburyo bwo kwita ku ruhu. Mu nzira yo gukurikirana ubwiza nubuzima, DL panthenol izakomeza kugira uruhare rwayo rwihariye kandi rwingenzi, yandika igice gishya mubumenyi bwuruhu.
Igihe cyo kohereza: Werurwe-18-2025
