Mugukurikirana imiterere yumucyo ndetse nuruhu, ibintu byera bihora bitangizwa, kandi arbutine, nkimwe mubyiza, yakwegereye cyane kubituruka kumiterere yabyo n'ingaruka zikomeye. Ibi bikoresho bifatika byakuwe mubihingwa nk'imbuto z'imbuto n'igiti cy'isaro byahindutse uruhare rukomeye kandi rukomeye mu kwera no kuvura uruhu rwa kijyambere. Iyi ngingo izacengera muburyo bwo kwera bwa arbutine, imikorere yayo yemewe na siyansi, nuburyo bwo kuyinjiza neza kandi neza mubikorwa bya buri munsi byo kuvura uruhu.
1 mechanism Uburyo bwo kwera bwaarbutin
Ingaruka yera ya arbutin ituruka kumiterere yihariye ya molekile n'inzira y'ibikorwa. Nubwoko bwa glucoside ivanze, arbutine irashobora guhatanira guhagarika ibikorwa bya tyrosinase, enzyme yingenzi mugikorwa cya melanin. Bitandukanye nibintu bimwe na bimwe bikomeye ariko bishobora gutera uburakari, arbutin ibangamira buhoro buhoro guhindura dopa kuri dopaquinone, bityo bikagabanya umusaruro wa melanin ku isoko.
Ubushakashatsi bwerekanye ko arbutine igira ingaruka ziterwa no guhagarika, kandi ubushobozi bwo guhagarika α - arbutine ni bwiza cyane kuruta β - isomer. Iyo ushyizwe kuruhu, arbutin irekura buhoro buhoro hydroquinone, ariko irekurwa riratinda kandi rirashobora kugenzurwa, wirinda kurakara ningaruka zishobora kuba nyinshi za hydroquinone. Byongeye kandi, arbutine irashobora kubuza ikwirakwizwa rya melanocytes no kwimura uduce duto twa melanin dukuze kuri keratinocytes, bikagera ku kurinda urwego rwera.
2 ver Clinical efficacy verisiyo ya arbutin
Ubushakashatsi bwinshi bwa siyansi bwemeje imikorere idasanzwe ya arbutine mugutezimbere ibibazo bitandukanye bya pigmentation. Mu bushakashatsi bw’ubuvuzi bwibyumweru 12, amasomo akoresha ibicuruzwa birimo 2% alpha arbutine yerekanaga igabanuka ryibara ryinshi hamwe no kumurika uruhu muri rusange, nta ngaruka mbi zigeze zivugwa. Ubushakashatsi bugereranije bwerekanye ko arbutine igereranywa nibintu bimwe na bimwe byera byera mugutezimbere melasma, izuba, hamwe na pigmentation yumuriro, ariko bifite kwihanganira neza.
Ingaruka yera ya arbutine mubisanzwe itangira kwerekana nyuma yibyumweru 4-8 byo gukoresha, kandi gukoresha ubudahwema bishobora kugera kumajyambere. Birakwiye ko tumenya ko arbutine idashobora koroshya gusa pigmentation iriho, ariko kandi ikabuza no gushiraho pigmentation nshya, bigatuma ihitamo neza mugucunga neza kwera. Iyo ikoreshejwe ifatanije nibindi bintu byera nka vitamine C, niacinamide, cyangwa quercetin, arbutine irashobora gutanga imbaraga zo guhuza imbaraga, bikongera ingaruka zose zo kwera.
3 Ibitekerezo byo guhitamo no gukoresha ibicuruzwa bya arbutin
Hariho ubwoko butandukanye bwaarbutinibicuruzwa ku isoko, kandi abaguzi bagomba kwitondera ibipimo byinshi byingenzi kugirango barebe ubuziranenge. Ibicuruzwa byujuje ubuziranenge bigomba kwerekana neza ubwoko bwa arbutine (cyane cyane alpha arbutin) hamwe nibitekerezo (mubisanzwe hagati ya 1-3%), kandi bigakoresha ibipfunyika bihamye kugirango wirinde gufotora. Ibicuruzwa birimo antioxydants nka vitamine E birashobora gukomeza neza ibikorwa bya arbutine.
Iyo winjije arbutine mubuvuzi bwuruhu rwa buri munsi, birasabwa gutangirira kumitekerereze mike hanyuma ugashyiraho kwihanganira buhoro buhoro. Igihe cyiza cyo gukoresha ni mugihe cya nimugoroba cyo kwita ku ruhu, rushobora guhuzwa nibicuruzwa bitanga amazi kugirango byongere kwinjira. Nubwo arbutine ifite ubwitonzi buhanitse, birakenewe gushimangira kurinda izuba iyo bikoreshejwe kumanywa. Birasabwa kubihuza hamwe nizuba ryagutse ryizuba hamwe na SPF30 cyangwa irenga. Birakwiye ko tumenya ko arbutine idakwiriye gukoreshwa icyarimwe hamwe nibicuruzwa bya aside irike cyane kugirango birinde kugira ingaruka kumutekano wacyo.
Arbutin, hamwe nibisanzwe, ikora neza, kandi yoroheje, ifite umwanya udasimburwa murwego rwo kwera. Yaba ikoreshwa wenyine cyangwa ifatanije nibindi bikoresho bikora, arbutin irashobora gutanga amahitamo meza kandi yizewe kubantu bakurikirana uruhu rwiza. Hamwe niterambere ryikoranabuhanga ryita kuruhu, tekinoroji yo gutegura arbutin ihora ari udushya. Mu bihe biri imbere, turateganya kubona ibicuruzwa byiza bya arbutine bikora neza kandi bihamye, bikazana ubwo butunzi karemano kubantu benshi bita kubantu. Guhitamo neza no gukoresha neza, arbutin izakubera umufasha wawe wizewe murugendo rwo kwera.
Igihe cyo kohereza: Werurwe-31-2025
