Kurwanya inflammatory na antioxidant uburyo bubiri - uburyo bwo kwita ku ruhu karemano, phloretin！

1.-Florine ni iki?

Phloretin(Izina ry'icyongereza: Phloretin), rizwi kandi nka trihydroxyphenolacetone, ni irya dihydrochalcones muri flavonoide. Yibanze muri rhizomes cyangwa imizi ya pome, strawberry, amapera nizindi mbuto n'imboga zitandukanye. Yiswe uruhu. Irashobora gushonga mumuti wa alkali, gushonga byoroshye muri methanol, Ethanol na acetone, kandi hafi yo kudashonga mumazi.

Phloretine irashobora kwinjizwa mu buryo butaziguye n'umubiri w'umuntu, ariko mu bimera, usanga floretine iba nkeya cyane. Phloretin ibaho cyane muburyo bwa glycoside ikomoka, phlorizine. Floretine yakiriwe numubiri wumuntu iri mumitsi yo munda. Gusa nyuma ya glycoside itsinda ryakuweho kugirango habeho phloretin irashobora kwinjira muri sisitemu yo kuzenguruka no gukora ingaruka zayo.

Izina ryimiti: 2,4,6-trihydroxy-3- (4-hydroxyphenyl) propiophenone

Inzira ya molekulari: C15H14O5

Uburemere bwa molekuline: 274.27

2.-Ibikorwa byingenzi bya phloretin-

anti-okiside

Flavonoide ifite ibikorwa byo kurwanya ibinure byo kurwanya ibinure, byemejwe nko mu myaka ya za 1960: imiterere ya polyhydroxyl ya flavonoide nyinshi ishobora kugira antioxydants ikomeye mu gukonjesha ioni.

Phloretin ni antioxydants nziza cyane. Imiterere ya 2,6-dihydroxyacetophenone ifite ingaruka nziza cyane ya antioxydeant. Ifite ingaruka zigaragara kuri scaringing peroxynitrite kandi ifite antioxydants nyinshi mumavuta. Hagati ya 10 na 30PPm, irashobora gukuraho radicals yubusa kuruhu. Ibikorwa bya antioxydeant ya Phlorizin bigabanuka cyane kuko hydroxyl yayo kumwanya wa 6 isimburwa nitsinda rya glucosidyl.
Kubuza tyrosinase

Tyrosinase ni umuringa urimo metalloenzyme kandi ni enzyme y'ingenzi mu mikorere ya melanin. Igikorwa cya tyrosinase kirashobora gukoreshwa mugusuzuma niba ibicuruzwa bifite ingaruka zera. Phloretin ni isubiranamo ryivanze rya tyrosinase. Irashobora kubuza tyrosinase guhuza na substrate yayo ihindura imiterere ya kabiri ya tyrosinase, bityo igabanya ibikorwa byayo.

Igikorwa cya antibacterial

Phloretin nuruvange rwa flavonoid hamwe nibikorwa bya antibacterial. Ifite ingaruka mbi kuri bagiteri zitandukanye za Gram-positif, Gram-negative bacteria na fungi.
Ibisubizo byubuvuzi byerekana ko nyuma yamasomo yakoresheje phloretin mugihe cibyumweru 4, imitwe yera, umukara, papula, hamwe na sekum ya sebum yagabanutse cyane, byerekana ko phloretin ifite ubushobozi bwo kugabanya acne.

3. Ibikoresho byasabwe
ishingiro
2% phloretin(antioxydeant, yera) + 10% [aside aside] (antioxydeant, kuzamura kolagen no kwera) + 0.5%acide ferulic.